Binding of prazosin and propranolol at variable alpha 1-acid glycoprotein and albumin concentrations.
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چکیده
منابع مشابه
Interactions of Linezolid with Two Major Serum Proteins, Human Serum Albumin and Alpha-1 Acid Glycoprotein
Linezolid (LZD) is an oxazolidinone antibiotic agent that acts against gram-positive bacteria. It was recently reported that LZD can induce severe hematologic toxicity, which is thought to result in high LZD concentrations in plasma. Although many factors can affect the disposition of drugs, the binding of drug to plasma proteins, such as albumin and alpha1-acid glycoprotein (AGP), is one of th...
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HIV protease inhibitors are an important component of highly active antiretroviral therapy used to treat pregnant women infected with HIV. They have a low placental transfer and are highly plasma protein bound. This study was carried out to determine the unbound fraction of lopinavir in cord blood, and to characterize the binding of lopinavir to 1-acid glycoprotein (AAG) and human serum albumin...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1989
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1989.tb05355.x